Table 1.

Cell cycle regulatory network interaction list. Connectivity value is included in parentheses next to each regulatory gene and represents the number of node connections associated with each regulatory gene.

CDK2 (49)	PCNA (40)	RPA1 (39)	CDK1 (35)	BRCA1 (32)	MCM2 (32)
PA2G4	USP1	TIPIN	TIPIN	ORC2	RPA3
PAICS	TIMELESS	EXOSC8	EXOSC8	MSH6	ORC2
MYBL2	POLD3	SMC4	SMC4	CCNB1	PLK1
HMGA1	POLD2	TMPO	TMPO	H2AFX	CDK6
CCNE2	POLD1	CHTF18	CHTF18	HMMR	ORC5
HMGB2	RPA1	UNG	UNG	CDK4	L3MBTL1
CDKN3	RPA2	NOP56	NOP56	TUBB	MCM7
CKS2	RPA3	RFC2	RFC2	EZH2	ORC4
CCNA1	RFC2	RFC3	RFC3	MYC	MCM5
CDC25A	RFC3	SNRPB	SNRPB	UBE2T	GINS3
GMNN	CHTF18	RPA3	RPA3	MLH1	CDC6
CKS1B	HUS1	PAN2	PAN2	DBF4	CDK4
CDC20	MLH1	RPA2	RPA2	MSH3	ORC6
CDC7	DSCC1	POLD1	POLD1	CHEK2	MCM3
DBF4	POLE	PCNA	PCNA	RBBP7	DBF4
MCM4	UNG	TOP2A	TOP2A	DDX39A	CCNB2
MCM6	PMS2	MSH3	MSH3	ORC3	CDC45
CDC45	TOP2A	HUS1	HUS1	BARD1	MCM4
ORC2	MSH3	RAD9A	RAD9A	CDKN2A	CKS2
MCM7	MSH6	MSH6	MSH6	TOP2A	CDKN2A
ORC1	RAD9A	MSH2	MSH2	RPA1	RPA1
CDC6	DNMT1	ATR	ATR	TP53	ASF1B
CDT1	MSH2	BRCA1	BRCA1	TUBG1	MCM10
CDKN1A	CHEK1	TK1	TK1	MSH2	RPA2
CCNB1	BARD1	CDK1	CDK1	ATR	ATR
CDK1	CDK6	CCNB1	CCNB1	CHEK1	ORC1
TUBG1	LIG1	CCNA1	CCNA1	CDK1	CCNA1
LMNB1	CDKN2A	ORC6	ORC6	CCNA1	CDC7
CCNB2	TP53	MCM4	MCM4	CCND1	MMS22L
CCND1	CDK4	MCM6	MCM6	AURKA	CCND1
MCM2	CCND3	MCM7	MCM7	CDK2	MCM6
MCM3	CCND1	MCM2	MCM2	RFC2	CDK2
POLD1 POLD2	CDK2 CDC6	MCM3 ORC2	MCM3 ORC2
RPA1	CDKN1A	CDK2	CDK2
PCNA	CCNB2	CDC5L	CDC5L
BRCA1	CDK1	TP53	TP53
TUBB CDC5L	CCNB1 CDT1	TUBB RRM2	TUBB RRM2
BIRC5	L3MBTL1
CCND3
CDK6
MSH2 SMC4