Figure 4.

Stratification of circulating betatrophin/ANGPTL8 according to hypertriacylglyceridemia. Levels of circulating betatrophin/ANGPTL8 were significantly increased exclusively in septic patients with concurrent hypertriacylglyceridemia > 1.7 mmol/l (“yes”, n = 7) compared to septic subjects and controls with absent dyslipidemia (“no”, n = 6 and n = 15, respectively; p = 0.017 and p = 0.0015 after post hoc correction, overall significance according to Kruskal–Wallis p = 0.0025). No significant effects became apparent in the insulin-resistance group (p > 0.05; “yes”, n = 21; “no”, n = 11). IR, insulin resistance. * p < 0.05, ** p < 0.01 in Kruskal-Wallis test and post-hoc Dunn correction.