Table 1.
Frequency | Univariable Cox Regression | Multivariable Cox Regression | |||||||
---|---|---|---|---|---|---|---|---|---|
Characteristic | Overall, 1 n = 375 | Alive, 1 n = 344 | Deceased, 1 n = 31 | HR 2 | 95% CI 2 | p | HR | 95% CI | p |
Fe level in quarters (µg/L) | |||||||||
I (162.15–893.05) | 94 (25%) | 82 (24%) | 12 (39%) | 4.12 | 1.16, 14.6 | 0.028 | 4.66 | 1.28, 16.9 | 0.019 |
II (895.69–1095.88) | 93 (25%) | 86 (25%) | 7 (23%) | 2.35 | 0.61, 9.10 | 0.2 | 3.40 | 0.85, 13.6 | 0.083 |
III (1105.49–1346.75) | 94 (25%) | 85 (25%) | 9 (29%) | 3.12 | 0.84, 11.5 | 0.088 | 3.71 | 0.99, 13.9 | 0.052 |
IV (1348.63–2815.78) | 94 (25%) | 91 (26%) | 3 (9.7%) | — | — | — | — | ||
Sex | |||||||||
Female | 231 (62%) | 217 (63%) | 14 (45%) | — | — | — | — | ||
Male | 144 (38%) | 127 (37%) | 17 (55%) | 2.09 | 1.03, 4.24 | 0.042 | 1.88 | 0.90, 3.92 | 0.092 |
Age | 21.00–90.00 (54.63) | 21.00– 90.00 (53.76) | 38.00 – 86.00 (64.26) | 1.06 | 1.03, 1.09 | <0.001 | 1.05 | 1.02, 1.09 | <0.001 |
Breslow (mm) * | 0.20–16.80 (1.80) | 0.20–16.80 (1.71) | 0.50–11.00 (3.22) | 1.16 | 1.04, 1.29 | 0.008 | 1.11 | 0.96, 1.28 | 0.2 |
Clark | |||||||||
II | 71 (19%) | 70 (20%) | 1 (3.2%) | — | — | — | — | ||
III | 157 (42%) | 145 (42%) | 12 (39%) | 5.47 | 0.71, 42.1 | 0.10 | 4.35 | 0.56, 33.7 | 0.2 |
IV/V | 147 (39%) | 129 (38%) | 18 (58%) | 8.76 | 1.17, 65.7 | 0.035 | 6.84 | 0.91, 51.7 | 0.062 |
1 n (%); range (Mean); 2 HR = hazard ratio, CI = confidence interval; * n = 324.