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. 2022 Nov 23;10(12):3018. doi: 10.3390/biomedicines10123018

Table 1.

Characteristics of the study group and uni- and multivariable Cox proportional hazard models for given factors (n = 375).

Frequency Univariable Cox Regression Multivariable Cox Regression
Characteristic Overall, 1 n = 375 Alive, 1 n = 344 Deceased, 1 n = 31 HR 2 95% CI 2 p HR 95% CI p
Fe level in quarters (µg/L)
I (162.15–893.05) 94 (25%) 82 (24%) 12 (39%) 4.12 1.16, 14.6 0.028 4.66 1.28, 16.9 0.019
II (895.69–1095.88) 93 (25%) 86 (25%) 7 (23%) 2.35 0.61, 9.10 0.2 3.40 0.85, 13.6 0.083
III (1105.49–1346.75) 94 (25%) 85 (25%) 9 (29%) 3.12 0.84, 11.5 0.088 3.71 0.99, 13.9 0.052
IV (1348.63–2815.78) 94 (25%) 91 (26%) 3 (9.7%)
Sex
Female 231 (62%) 217 (63%) 14 (45%)
Male 144 (38%) 127 (37%) 17 (55%) 2.09 1.03, 4.24 0.042 1.88 0.90, 3.92 0.092
Age 21.00–90.00 (54.63) 21.00– 90.00 (53.76) 38.00 – 86.00 (64.26) 1.06 1.03, 1.09 <0.001 1.05 1.02, 1.09 <0.001
Breslow (mm) * 0.20–16.80 (1.80) 0.20–16.80 (1.71) 0.50–11.00 (3.22) 1.16 1.04, 1.29 0.008 1.11 0.96, 1.28 0.2
Clark
II 71 (19%) 70 (20%) 1 (3.2%)
III 157 (42%) 145 (42%) 12 (39%) 5.47 0.71, 42.1 0.10 4.35 0.56, 33.7 0.2
IV/V 147 (39%) 129 (38%) 18 (58%) 8.76 1.17, 65.7 0.035 6.84 0.91, 51.7 0.062

1 n (%); range (Mean); 2 HR = hazard ratio, CI = confidence interval; * n = 324.