Table 1.
Demographic, clinical, and laboratory parameter data of all enrolled subjects.
| Demographic and Clinical Characteristics | AD | non-AD | Controls | p-Value |
p-Value after the Bonferroni Correction |
|---|---|---|---|---|---|
| Gender M/F (%) | 8/10 (44/56) | 30/34 (44/56) | 7/11 (39/61) | 0.843 | - |
| Age (years ±SD) | 72.13 ± 5.45 | 69.34 ± 7.48 | 65.67 ± 12.02 | 0.08 | - |
| Disease duration (years ±SD) | 2.83 ± 2.28 | 2.65 ± 2.88 | - | 0.79 | - |
| MMSE (±SD) | 22.47 ± 3.78 | 23.66 ± 3.95 | - | 0.34 | - |
| CSF and saliva biomarkers | AD | non-AD | Controls | p-Value |
p-Value after the Bonferroni correction |
| t-tau [pg/mL] (±SD) | 299.50 ± 317.12 | 157.48 ± 144.94 | 86.83 ± 65.75 | 0.002 ** | AD vs. non-AD 0.011 * AD vs. Controls 0.002 ** |
| p-tau [pg/mL] (±SD) | 60.11 ± 43.53 | 40.8 ± 40.86 | 26.28 ± 12.80 | 0.025 * | AD vs. non-AD 0.18 AD vs. Controls 0.027 * |
| Aβ42 CSF [pg/mL] (±SD) | 454.39 ± 51.86 | 903.28 ± 311.60 | 1127.61 ± 358.85 | 0.000 *** | AD vs. non-AD <0.001 *** AD vs. Controls <0.001 *** |
| Aβ42 saliva [pg/mL] (±SD) | 127.11 ± 33.44 | 88.03 ± 39.04 | 66.11 ± 24.82 | 0.000 *** | AD vs. non-AD <0.001 *** AD vs. Controls <0.001 *** |
The following codes define different significance levels: “***” for p < 0.001; “**” for p < 0.01; and “*” for p < 0.05.