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. 2022 Dec 19;10(12):3282. doi: 10.3390/biomedicines10123282

Table 1.

Encapsulation Efficiency, Particle Size, Polydispersity Index, and Zeta Potential of Ciprofloxacin (CPX)-Loaded Chitosan Nanoparticles (n = 5).

CS/TPP Weight Ratio Ciprofloxacin Hydrochloride (mg/mL) Average Particle Size (nm) Polydispersity (PDI) Zeta Potential (mV) Encapsulation Efficiency (%)
5:1 (CS 1 mg/mL) & TPP (0.5 mg/mL)
Formulation 1
0.5 195.6 ± 11 0.249 +24.86 ± 1.2 43 ± 2.29%
1 185.5 ± 2 0.217 +24.91 ± 0.6 42 ± 2.35%
5:1 (CS 2 mg/mL) & PP (1 mg/mL)
Formulation 2
0.5 214.8 ± 8 0.249 +29.6 ± 0.8 46 ± 2.15%
1 252.9 ± 9 0.254 +27.0 ± 0.7 43 ± 2.27%
9:1 (CS 1 mg/mL) & TPP (1 mg/mL)
Formulation 3
0.5 229.1 ± 13 0.250 +28.35 ± 2.6 43 ± 2.25%
1 235.4 ± 16 0.289 +29.31 ± 2.1 43 ± 4.54%