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. 2022 Dec 9;12(12):1842. doi: 10.3390/biom12121842

Figure 1.

Figure 1

Stand-alone dynamics of two-node and three-node mutually repressing motifs. (A) A toggle switch (TS) motif comprises two nodes A and B that mutually inhibit each other. (B) Probability density plot of steady state values of nodes in a TS. The two dense clusters correspond to “single-positive” 01 and 10 steady states (F1) of a TS. (C) Regression plot between the steady states values of two nodes, A and B of a TS. Correlation coefficient (CC AB) between them is −0.83. (D) A toggle triad (TT) motif comprises three mutually repressing nodes A, B, and C. (E) Probability density plot of steady-state values of two TT nodes A and B; the three clusters represent three “single-positive” steady states (F1), 001, 010, and 100. (F) Regression plot between steady state values of nodes B and C of a TT. Correlation coefficient (CC BC) = −0.39. Other pairwise correlation coefficient values are also mentioned: CC (AC) = −0.39, CC (AB) = −0.40.