Table 2.
Demographic and clinical characteristics of the participants.
| CBS (n = 14) |
CBS-Non-AD (n = 10) |
CBS-AD (n = 4) |
CG (n = 15) |
CBS vs. CG p-Value |
CBS-Non-AD vs. CBS-AD vs. CG p-Value |
|
|---|---|---|---|---|---|---|
| Age (y) | 67.9 (8.4) | 66.4 (8.3) | 71.5 (8.7) | 67.3 (8.1) | 0.813 | 0.746 |
| Education (y) | 8.8 (5.8) | 9.3 (5.9) | 7.5 (6.0) | 9.3 (5.4) | 0.914 | 0.875 |
| Sex (F/M) | 9/5 | 5/5 | 4/0 | 10/5 | 0.892 | 0.203 |
| Hand dominance (R/L) | 12/2 | 8/2 | 4/0 | 14/1 | 0.500 | 0.430 |
| Symptom duration (y) | 4.6 (2.1) | 4.7 (2.4) | 4.5 (1.2) | -- | -- | 0.770 * |
| CDR | 1.9 (0.7) | 1.9 (0.7) | 2.0 (0.8) | -- | -- | 0.941 * |
| FAQ | 19.9 (7.8) | 18.6 (7.6) | 23.0 (8.4) | -- | -- | 0.337 * |
| NPI | 17.2 (16.7) | 12.9 (8.7) | 26.7 (27.1) | -- | -- | 0.394 * |
| H&Y | 2.9 (1.3) | 3.0 (1.3) | 2.7 (1.7) | -- | -- | 0.774 * |
Note: Comparison analyses across all groups were performed using ANOVA (normally distributed data) or the Kruskal–Wallis test (non-normal distribution). The CBS vs. CG and CBS-non-AD vs. CG were carried out using Student’s t-test (normal) or the Mann–Whitney test (non-normal). * CBS-non-AD vs. CBS-AD comparison using the t-test or the Mann–Whitney test. Sex and hand dominance were compared across groups using chi-squared test. Data are reported as the mean (SD). Abbreviations: CBS = corticobasal syndrome, CBS-non-AD = corticobasal syndrome not related to Alzheimer’s disease, CBS-AD = corticobasal syndrome related to Alzheimer’s disease; SD = standard deviation, y = years, CDR = Clinical Dementia Rating, FAQ = Functional Activities Questionnaire, NPI = Neuropsychiatric Inventory, and H&Y = Hoehn and Yahr scale.