Table 2.
Regional activations to win > nil and loss > nil in correlation with AUDIT and BDI-II scores with age, sex, and FTND score as covariates.
| Volume (mm3) |
Peak Z | MNI Coordinate (mm) | Side | Identified Brain Region | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Regression with AUDIT | ||||||
| Positive with Win > Nil | ||||||
| 100,845 | 5.34 | −15 | 29 | 43 | L/R | DLPFC, SFG, Precentral G, SMA |
| 4.84 | 36 | −31 | 40 | L/R | IPL, PCC, Precuneus | |
| 49,815 | 5.27 | −21 | −37 | −11 | L | Hippocampus, Amygdala |
| 5.21 | 54 | −46 | −5 | R | Temporal G | |
| 6669 | 4.48 | 6 | 41 | 13 | L/R | ACC |
| 2862 | 4.06 | −9 | −7 | −11 | L/R | Hypothalamus |
| 2511 | 3.85 | −33 | 32 | 4 | L | IFG |
| Negative with Win > Nil | ||||||
| 4266 | 4.06 | 6 | −70 | −35 | L/R | CBL |
| Positive with Loss > Nil | ||||||
| 68,796 | 5.97 | 54 | −31 | −8 | R | Temporal G, Hippocampus, Amygdala, Hypothalamus |
| 5.29 | −12 | −58 | −20 | L | CBL | |
| 84,375 | 5.10 | 18 | −46 | 40 | L/R | Precuneus, DLPFC, MPFC, MCC |
| 4.90 | 60 | −55 | 31 | R | IPL, Precentral G, | |
| 3078 | 4.49 | −33 | 11 | −8 | L | Insula |
| 4806 | 4.30 | −33 | −1 | 40 | L | Precentral gyrus |
| 2538 | 4.30 | 9 | 59 | −5 | R | VMPFC |
| Negative with Loss > Nil | ||||||
| None | ||||||
| Regression with BDI | ||||||
| Positive with Win > Nil | ||||||
| 54,324 | 4.95 | 21 | −7 | −17 | R | Hippocampus, Amygdala, Hypothalamus |
| 4.76 | 45 | −43 | −14 | R | Temporal G | |
| 33,696 | 4.63 | −6 | −40 | 40 | L | Precuneus, PCC, DLPFC, SFG, SMA |
| 6048 | 4.57 | 57 | −61 | 34 | R | IPL |
| 4401 | 4.29 | −42 | −40 | 34 | L | IPL |
| 6399 | 4.26 | −12 | 23 | 40 | L | SFG |
| Negative with Win > Nil | ||||||
| None | ||||||
| Positive with Loss > Nil | ||||||
| 10,665 | 4.89 | −18 | −10 | −20 | L | Hippocampus, Amygdala, Temporal G |
| 25,326 | 4.81 | 24 | −10 | −14 | R | Hippocampus, Amygdala, Temporal G, CBL |
| 6399 | 4.21 | 63 | −46 | 37 | R | IPL |
| 4320 | 4.08 | 21 | 59 | 22 | R | SFG |
| 4158 | 3.84 | −9 | −7 | 34 | L | MCC |
| 2403 | 3.67 | −6 | −37 | 40 | L | MCC |
| Negative with Loss > Nil | ||||||
| None | ||||||
Note: Results were evaluated at voxel p < 0.001 and cluster-level p < 0.05, FWE corrected; L: left; R: right; G: gyrus; Cerebellum: CBL; DLPFC: dorsolateral prefrontal cortex; SFG: superior frontal gyrus, IPL: inferior parietal lobule; PCC: posterior cingulate cortex; ACC: anterior cingulate cortex; IFG: inferior frontal gyrus; MPFC: medial prefrontal cortex; MCC: mid-cingulate cortex; VMPFC: ventromedial prefrontal cortex; SMA: supplementary motor area.