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. 2022 Dec 9;12(12):1689. doi: 10.3390/brainsci12121689

Table 3.

Mediation models of AUDIT, BDI-II score, and brain activation (β) each for win > nil and loss > nil.

p Values
X M Y X → M M → Y X → Y Mediated X → Y Mediation
Win > Nil
AUDIT BDI Brain <0.001 0.006 <0.001 <0.001 0.021
Brain BDI AUDIT <0.001 0.190 <0.001 <0.001 0.204
AUDIT Brain BDI <0.001 0.006 <0.001 0.190 0.013
BDI Brain AUDIT <0.001 <0.001 <0.001 0.190 0.005 *
Brain AUDIT BDI <0.001 0.190 <0.001 0.006 0.201
BDI AUDIT Brain <0.001 <0.001 <0.001 0.006 0.009
Loss > Nil
AUDIT BDI Brain <0.001 0.010 <0.001 <0.001 0.029
Brain BDI AUDIT <0.001 0.149 <0.001 <0.001 0.166
AUDIT Brain BDI <0.001 0.010 <0.001 0.149 0.020
BDI Brain AUDIT <0.001 <0.001 <0.001 0.149 0.006 *
Brain AUDIT BDI <0.001 0.149 <0.001 0.010 0.162
BDI AUDIT Brain <0.001 <0.001 <0.001 0.010 0.009

Note: The mediation models were evaluated at a corrected p = 0.05/6 = 0.0083. * p < 0.0083. A significant mediation and non-significant mediated X Y suggest that M completely mediates the correlation of X and Y.