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. 2022 Dec 15;12(12):1171. doi: 10.3390/bios12121171

Figure 3.

Figure 3

Schematic detection principle of E. coli hydrogenated amorphous silicon a-Si:H surface modified with anti-fimbrial antibodies against the major pilin protein fimA. (a) Surface structures of E. coli expressing fimA selectively captured and positively charged Au-NRs incubated with E. coli for SERS sensing. (b) Anti-fimbriae modified array, optical imaging of spots after interaction with E. coli and SERS spectra after capturing bacteria [97]. Adapted with permission from Ref. [97]. Copyright © 2020 Elsevier B.V.