Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 12;12(12):1855. doi: 10.3390/biom12121855

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Reconstruction of a cell trajectory by monocle single-cell trajectory analysis. (A) Monocle reconstructed two main branches from a single cell trajectory. Branch 1 contains cluster 1 and cluster 4, branch 2 contains cluster 2 and cluster 5. Cells are colored based on state (left), and cluster (right). Cells in different branches have different cellular differentiation characteristics. (B–E) Gene ontology (GO) enrichment analysis and KEGG pathway analysis for branch−dependent genes. GO enrichment analysis (B) and KEGG pathway analysis (D) of differentially expressed genes (DEGs) in branch1. GO enrichment analysis (C) and KEGG pathway analysis (E) of DEGs in branch2.