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Effect of anti-CD28 treatment on intra-abdominal abscess formation by B. fragilisa
| Treatment | No. of animals positive for abscesses/total (%) | P |
|---|---|---|
| Saline | 8/19 (42) | |
| Anti-CD28b | 15/18 (83) | <0.02 |
A dose of B. fragilis (5 × 107 CFU/animal) was used to induce abscesses in approximately 50% of animals.
A dose of 500 μg/ml was administered via the intracardiac route.
