Table 1.
IC50 values for CBG variants in Colorectal Cancer Cell Lines.
| Cell Line | CBGV | CBGB | CBG | CBGP | CBGN |
|---|---|---|---|---|---|
| SW480 | 12.3 ± 2.5 ** | 15.5 ± 2.1 * | 22.8 ± 3.4 | 23.9 ± 5.0 | 24.5 ± 6.0 |
| SW620 | 8.1 ± 0.6 * | 13.6 ± 1.7 | 16.2 ± 1.3 | 20.6 ± 3.6 | 23.4 ± 7.8 |
| HT29 | 5.6 ± 3.3 ** | 12.5 ± 4.7 | 16.6 ± 3.3 | 25.2 ± 4.1 * | 20.8 ± 3.6 |
| DLD-1 | 8.3 ± 1.6 | 15.4 ± 1.4 ** | 7.9 ± 1.2 | 20.2 ± 3.9 *** | 19.4 ± 3.7 *** |
| HCT116 | 9.3 ± 1.6 **** | 15.8 ± 1.6 *** | 21.6 ± 1.4 | 22.9 ± 0.1 | 22.3 ± 1.0 |
| LS174 | 9.4 ± 1.1 *** | 14.0 ± 3.1 | 16.7 ± 2.3 | 18.2 ± 1.1 | 17.3 ± 1.9 |
| RKO | 9.1 ± 2.9 ** | 13.1 ± 0.7 | 14.7 ± 0.5 | 17.5 ± 1.6 | 19.0 ± 1.6 * |
IC50 values are from 3–4 independent dose effect curves and are presented as mean ± standard deviation, concentrations are in µM. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.005, **** p ≤ 0.001 vs. CBG.