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. 2022 Nov 30;12(12):1789. doi: 10.3390/biom12121789

Figure 1.

Figure 1

DIVERSet ATPase screen for SERCA effectors. (A) Percent change in ATPase activity for 46K compound screen. Selected activating compounds displayed in red. (B) Gaussian fit of percent effect distribution. (C) CV% for each assay plate. (D) Numbers of SERCA activating and inhibiting compounds that meet various SD thresholds above (activators) or below (inhibitors) the mean.