Figure 5.

Effects of Arecae Pericarpium ethanol extract on the activation of antioxidant enzymes in glutamate-exposed HT22 cells. The cells were incubated with 5 mM glutamate with or without APE. The expression levels of catalase, GCLC subunits, and NQO1 were determined via Western blot analysis. Control was non-treated cells. Blot images represent the three independent experiments. Data were presented as mean ± standard error of the mean. Statistical significance was set at # p < 0.05 (vs. control), * p < 0.05, ** p < 0.01, and † p < 0.001 (vs. glutamate). APE, Arecae Pericarpium ethanol extract; Con, control; GCLC, glutamate-cysteine ligase catalytic; Glu, glutamate; NQO1, NAD(P)H quinone oxidoreductase 1.