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. 2022 Dec 18;14(24):6244. doi: 10.3390/cancers14246244

Table 2.

Predictors for late relapse—multinominal logistic regression.

Variable Odds Ratio 95% CI p
Treatment prior to allo-SCT
Upfront #/CR vs.
No CR
3.402 1.140–10.155 0.028
ELN 2017//IPSS-R//CPSS
at diagnosis (14,16,18) *
Favorable/intermediate
Unfavorable
2.777 0.755–10.213 0.124
Karyotype
Not complex vs.
Complex
3.038 0.695–13.278 0.140

Odds ratio represents odds of late relapse versus odds of early relapse among patients who experienced relapse. # upfront: patients who proceeded to transplantation without prior cytoreductive chemotherapy, defined as no MDS- or AML-MRC-specific therapy except for growth factors, transfusions and a short period (<1 week) of hydroxyurea. * very good/good IPSS-R, favorable ELN and low CPSS risk groups were combined as one favorable disease risk group; intermediate IPSS-R, intermediate ELN and intermediate I/II CPSS formed one intermediate disease risk group; and high/very high IPSS-R, adverse ELN and high CPSS were summarized as one unfavorable disease risk group. The disease risk of patients with MDS, AML-MRC and CMML was estimated using IPSS-R, ELN 2017 classification and CPSS, respectively, and the respective subgroups were summarized as described above. Allo-SCT, allogeneic hematopoietic stem-cell transplantation; CI, confidence interval; CPSS, CMML-specific scoring system; CR, complete Remission; int, intermediate; ELN, European Leukemia Net; IPSS-R, International Prognostic Scoring System—Revised Version.