TABLE 1.
Health outcomes investigated
Health outcome or biochemical processes | No. of articles with studies in nonpregnant mice, n (%) | No. of articles with studies in pregnant mice, n (%) |
---|---|---|
Biochemical or metabolic pathway | 47 (24.6) | 14 (11.1) |
Cancer | 33 (17.3) | 8 (6.3) |
Cardiovascular | 23 (12.0) | 5 (4.0) |
Congenital defects | 0 (0.0) | 47 (37.3) |
Gastrointestinal and urinary disorders | 13 (6.8) | 9 (7.1) |
Genetic instability | 15 (7.9) | 29 (23.0) |
Immune response | 5 (2.6) | 1 (0.8) |
Liver disease | 13 (6.8) | 2 (1.6) |
Neurodegeneration | 42 (22.0) | 11 (8.7) |