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. 2022 Jul 12;13(6):2666–2678. doi: 10.1093/advances/nmac056

TABLE 1.

Health outcomes investigated

Health outcome or biochemical processes No. of articles with studies in nonpregnant mice, n (%) No. of articles with studies in pregnant mice, n (%)
Biochemical or metabolic pathway 47 (24.6) 14 (11.1)
Cancer 33 (17.3) 8 (6.3)
Cardiovascular 23 (12.0) 5 (4.0)
Congenital defects 0 (0.0) 47 (37.3)
Gastrointestinal and urinary disorders 13 (6.8) 9 (7.1)
Genetic instability 15 (7.9) 29 (23.0)
Immune response 5 (2.6) 1 (0.8)
Liver disease 13 (6.8) 2 (1.6)
Neurodegeneration 42 (22.0) 11 (8.7)