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. 2022 Sep 3;13(6):2329–2340. doi: 10.1093/advances/nmac072

TABLE 3.

Key findings evaluating the effects of Asp/Ace-K blends on human energy intake, appetite, blood glucose, and incretins when compared with sugar or water controls1

Outcomes Asp/Ace-K vs. controls
Energy intake • Asp/Ace-K < water (P = 0.002)
• Asp/Ace-K < sugar (P = 0.004)
Subjective appetite • 1 of 3 studies significantly found:Asp/Ace-K < water
• 2 of 3 studies no difference between groups
Blood glucose • No significant difference between Asp/Ace-K when compared with water and sugar controls
GLP-1 • No significant difference between Asp/Ace-K when compared with water and sugar controls
GIP • No significant difference between Asp/Ace-K when compared with water and sugar controls
1

Ace-K, acesulfame-K; Asp, aspartame; GIP, glucose-dependent insulinotropic peptide; GLP-1, glucagon-like peptide 1.