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Dose-response effect of CoQ10 supplementation on (A) systolic blood pressure and (B) diastolic blood pressure. The average curve (green solid line) with 95% confidence limits (red dotted lines) was estimated with a 1-stage random-effects restricted cubic spline model, using 0 mg/d as a reference. CoQ10, coenzyme Q10; DBP, diastolic blood pressure; SBP, systolic blood pressure.
