TABLE 13.
Summary of forest plot analyses of the effect of zinc supplementation in infants and children aged ≤3 y on lactulose:mannitol molar ratio, analyzed by duration, chemical formula, and comparator group1
| References | Mean difference | 95% CI | P | I 2 | ||
|---|---|---|---|---|---|---|
| By treatment duration | 0–3 mo | (60) | −0.08 | −0.15, −0.01 | NA | |
| >3 mo | (18) | −0.10 | −0.27, 0.07 | NA | ||
| Overall | −0.08 | −0.14, −0.02 | <0.001 | 0 | ||
| By chemical formula | Zn gluconate | (18) | −0.10 | −0.27, 0.07 | NA | |
| Zn acetate | (60) | −0.08 | −0.15, −0.01 | NA | ||
| Overall | −0.08 | −0.14, −0.12 | <0.001 | 0 | ||
| Zinc vs. placebo | (18, 60) | −0.08 | −0.14, 0.02 | 0.009 | 0 |
1
NA, not applicable.