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. 2022 Sep 2;13(6):2488–2518. doi: 10.1093/advances/nmac088

TABLE 7.

Summary of forest plot analyses of the effect of zinc supplementation in infants and children aged ≤3 y on iron deficiency (OR), analyzed by duration, chemical formula, and comparator group

References Mean difference 95% CI P I 2
By treatment duration 0–3 mo (73) 0.58 0.29, 1.18 NA
>3 mo (12, 29, 31, 34, 47, 53, 59, 70, 71) 1.02 0.77, 1.24 29
Overall 0.98 0.77, 1.24 0.87 32
By chemical formula Zn gluconate (73) 0.58 0.29, 1.18 NA
Zn sulfate (12, 29, 34, 47, 71) 1.14 0.82, 1.60 34
Not stated (31, 53, 70) 1.04 0.80, 1.34 0
Other (59) 0.97 0.37, 2.53 NA
Overall 1.01 0.83, 1.23 0.89 12
Zinc vs. placebo (12, 29, 53, 59, 70, 71) 1.04 0.79, 1.37 0.79 13

1NA, not applicable.