TABLE 9.
Summary of forest plot analyses of the effect of zinc supplementation in infants and children aged ≤3 y on serum/soluble transferrin receptor (mg/L), analyzed by duration, chemical formula, and comparator group1
| References | Mean difference | 95% CI | P | I 2 | ||
|---|---|---|---|---|---|---|
| By treatment duration | >3 mo | (12, 28, 36, 47, 74) | 0.19 | 0.08, 0.29 | <0.001 | 89 |
| By chemical formula | Zn sulfate | (12, 47) | 0.18 | 0.07, 0.29 | 97 | |
| Zn acetate | (28) | 0.44 | −1.08, 1.96 | 63 | ||
| Not stated | (36, 74) | 0.26 | −0.13, 0.65 | 0 | ||
| Overall | 0.19 | −0.08, 0.29 | <0.001 | 89 | ||
| Zinc vs. placebo and (ii) high-dose vs. low-dose zinc | (12, 28, 36, 47, 74) | 0.43 | −0.16, 0.93 | 0.08 | 76 | |
| High-dose vs. low-dose | (74) | −0.10 | −1.19, 0.99 | 0.86 | NA |
NA, not applicable.