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. 2022 Sep 2;13(6):2488–2518. doi: 10.1093/advances/nmac088

TABLE 9.

Summary of forest plot analyses of the effect of zinc supplementation in infants and children aged ≤3 y on serum/soluble transferrin receptor (mg/L), analyzed by duration, chemical formula, and comparator group1

References Mean difference 95% CI P I 2
By treatment duration >3 mo (12, 28, 36, 47, 74) 0.19 0.08, 0.29 <0.001 89
By chemical formula Zn sulfate (12, 47) 0.18 0.07, 0.29 97
Zn acetate (28) 0.44 −1.08, 1.96 63
Not stated (36, 74) 0.26 −0.13, 0.65 0
Overall 0.19 −0.08, 0.29 <0.001 89
Zinc vs. placebo and (ii) high-dose vs. low-dose zinc (12, 28, 36, 47, 74) 0.43 −0.16, 0.93 0.08 76
High-dose vs. low-dose (74) −0.10 −1.19, 0.99 0.86 NA
1

NA, not applicable.