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. 2022 Oct-Dec;19(10-12):29–34.

TABLE 1.

Summary of the main information present in the selected articles

AUTHORS TYPE OF STUDY SAMPLE SIZE (N) STROOP TEST RESULTS
Tröster et al17 Randomized study Total: 136; DBS: 101; control: 35 Declines in verbal fluency, processing speed, attention, and working memory. Greater decline in DBS patients.
Demeter et al24 Case-control study Total: 20; DBS: 10; control: 10 There was a significant difference in semantic fluency between the two groups.
Bouwyn et al1 Cohort study Total: 100; <65 years old: 57; >65 years old: 34 Significant decrease in verbal fluency tasks and increased interference time. The time to complete the task was longer in older participants.
Ardouin et al23 Cohort study Total: 62 Participants’ performance in Stroop was similar before and after DBS.
Witt et al29 Cohort study Total: 23 DBS patients committed more errors in the condition of Stroop interference.
Witt et al21 Randomized study Total: 123; DBS: 60; medication: 63 The DBS group had negative results in interference Stroop task and number of errors.
Jahanshahi et al30 Cohort study Total: 13 There was no significant difference in interference task. In control task (color), the patients with DBS were more rapid and presented a good number of self-corrections. Difference between STN and GPi.
Klempírová et al31 Cohort study Total: 19 Significant worsening of Stroop performance after DBS.
Acera et al12 Cohort study Total: 97; DBS: 50; control: 47 The patients did not show impairment in Stroop after DBS.
Sáez-Zea et al25 Cohort study Total: 36; DBS: 21; control: 12 There was no difference between the two groups. Slight worsening of fluency and color naming in Stroop in STN group.
Alegret et al26 Cohort study Total: 16; DBS: 9; medication: 7 Significant worsening of verbal fluency in DBS group. After 1 year, all but 1 participant presented decline in Stroop in relation to the initial performance.
Haegelen et al3 Cohort study Total: 71; GPi: 29; STN: 42 Stroop results in both groups suggested stability.
Heo et al20 Cohort study Total: 46 After DBS there was significant delay in word reading. After 1 year, delay in all Stroop tasks.
Witt et al22 Randomized study Total: 62; DBS: 31; medication: 31 No significant correlation was found in neuropsychological aspects.
Yamanaka et al13 Cohort study Total: 30 Significantly lower scores 1 month after STN. Recovered levels of performance 12 months after STN.
Hummelová et al33 Cohort study Total: 46 Significant decline in executive functions from Stroop.
Odekerken et al34 Randomized study Total: 114; GPi: 58; STN: 56 Significant differences in word reading and color naming in Stroop in STN individuals, showing greater negative change in relation to GPi.
Tramontana et al18 Randomized study Total: 30; medication: 15; DBS + medication: 15 In the first year after DBS, ODT group had better result in Stroop. There was no significant difference after 24 months.
Kim et al19 Cohort study Total: 36 Decline in the performance of the participants in Stroop was observed 36 months after surgery.
Kim et al35 Cohort study Total: 89 There was no significant difference in Stroop performance before and after surgery.
Witt et al28 Randomized study Total: 119; DBS: 60; medication: 59 The participants who had impaired Stroop performance also had high MDRS scores.
Gill et al36 Randomized study Total: 30; medication: 15; DBS + medication: 15 The participants described in the study did not show significant changes in Stroop after DBS.
Boel et al27 Randomized study Total= 128; GPi= 65; STN: 63 There was no significant difference in ST performance between the groups or over time.
Odekerken et al37 Randomized study Total= 128; GPi: 65; STN: 63 There was no significant difference in Stroop performance between the groups or over time.
Le Goff et al38 Cohort study Total: 59 Most of the participants increased the time in the Stroop task, suggesting executive dysfunctions.
Lefaucheur et al39 Cohort study Total: 18 In general, there was no performance decline in Stroop after DBS.
Bocková et al40 Case-control study Total: 8 Stroop was performed for preoperative screening. There was no sign of cognitive decline.
Smeding et al41 Cohort study Total: 145; STN: 105; control: 40 12 months after surgery, DBS group presented significant decline in Stroop score, compared to the control group.
Williams et al14 Randomized study Total: 37; STN:19; medication: 18 STN group showed decline in Stroop score in 2 years, when compared to the other group.
Weaver et al42 Randomized study Total: 225; DBS: 121; medication: 134 No intervention was associated with significant changes in Stroop score.
York et al15 Cohort study Total: 50; DBS: 23; control: 27 DBS group obtained worse performance in Stroop Word. Both groups declined in semantic fluency.
Rothlind et al43 Randomized study Total: 42; GPi: 23; STN: 19 Decline in Stroop score was observed after STN, compared to GPi.
Smeding et al16 Cohort study Total: 135; DBS: 99; control: 36 DBS group showed significant decline in Stroop score when compared to control.
Morrison et al44 Cohort study Total: 28; STN: 17; control: 11 Control group obtained better performance than DBS group in Stroop.
Alegret et al26 Cohort study Total: 15 Low performance in Stroop was evidenced 3 months after surgery.

DBS: Deep brain stimulation; STN: subthalamic nuclei; GPi: globus pallidus interna; MDRS: Mattis Dementia Rating Scale; ODT: optimal drug therapy; ST: Stroop test