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The expression of most of the key enzymes was downregulated in CRC. (A–H). The expression of these eight genes in colorectal cancer and normal colorectal tissues from UALCAN. (“ns” represents no significance, “**” represents p < 0.01, “***” represents p<0.001). The expression of five genes (ACADM, ACADS, GSR, HADH and HMGCL) in CRC were extremely lower than those in paired normal colorectal tissues (p < 0.001).
