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The deletion of ACADS promotes tumor growth and induces TAM polarization to M2 macrophages. (A). Mouse subcutaneous tumor model in Balb/c and Balb/cByJ mice. (B,C). Flow cytometry analysis of TAMs. (D). The expression of factors related with TAMs in tumor tissues was detected by qPCR. (E). The expression of factors related with TAMs in tumor tissues was detected by ELISA. (“*” represents p < 0.05, “**” represents p < 0.01, “***” represents p < 0.001).
