Table 4.
Upstream regulator list by IPA for w/ TNFα dataset.
Upstream Regulator | Expr Log Ratio | Molecule Type | Predicted Activation State | Activation z-Score | −log(p-Value) |
---|---|---|---|---|---|
TNF | −0.11 | Cytokine | Inhibited | −8.97 | 37.22 |
IL1B | −4.29 | Cytokine | Inhibited | −8.03 | 33.72 |
HIF1A | −0.73 | Transcription regulator | Inhibited | −5.95 | 26.64 |
IL33 | −2.61 | Cytokine | Inhibited | −4.58 | 19.20 |
NR3C1 | −0.16 | Ligand-dependent nuclear receptor | Activated | 2.19 | 19.09 |
NFkB (complex) | Complex | Inhibited | −7.07 | 19.03 |