Table 2.
Number and age-standardised incidence rate of total liver cancer, hepatocellular carcinoma, intrahepatic cholangiocarcinoma and ‘other liver cancer types’, by period of diagnosis, and percent distribution by histologic type (Italy, 2003–2017).
| Sex and Type | 2003–2017 | 2003–2007 | 2008–2012 | 2013–2017 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. | % | Rate * | (95% CI) | No. | Rate * | (95% CI) | No. | Rate * | (95% CI) | No. | Rate * | (95% CI) | |
| Men | |||||||||||||
| Total | 24,692 | 100.0% | 29.4 | (29.0; 29.8) | 7519 | 31.7 | (31.0; 32.4) | 8790 | 30.1 | (29.5; 30.8) | 8383 | 27.0 | (26.4; 27.6) |
| HCC | 12,343 | 50.0% | 14.6 | (14.3; 14.8) | 3757 | 15.6 | (15.1; 16.1) | 4339 | 14.7 | (14.3; 15.2) | 4247 | 13.6 | (13.2; 14.1) |
| ICC | 1531 | 6.2% | 1.8 | (1.7; 1.9) | 351 | 1.4 | (1.3; 1.6) | 513 | 1.7 | (1.6; 1.9) | 667 | 2.2 | (2.0; 2.3) |
| Other | 10,818 | 43.8% | 13.0 | (12.8; 13.3) | 3411 | 14.7 | (14.2; 15.2) | 3938 | 13.7 | (13.2; 14.1) | 3469 | 11.2 | (10.9; 11.6) |
| Women | |||||||||||||
| Total | 10,882 | 100.0% | 9.4 | (9.2; 9.6) | 3496 | 10.4 | (10.0; 10.7) | 3853 | 9.5 | (9.2; 9.8) | 3533 | 8.4 | (8.1; 8.7) |
| HCC | 3881 | 35.7% | 3.5 | (3.4; 3.6) | 1309 | 4.0 | (3.8; 4.2) | 1356 | 3.5 | (3.3; 3.7) | 1216 | 3.0 | (2.8; 3.2) |
| ICC | 1151 | 10.6% | 1.1 | (1.0; 1.2) | 269 | 0.9 | (0.8; 1.0) | 411 | 1.1 | (1.0; 1.2) | 471 | 1.2 | (1.1; 1.4) |
| Other | 5850 | 53.8% | 4.8 | (4.7; 5.0) | 1918 | 5.5 | (5.3; 5.8) | 2086 | 4.9 | (4.7; 5.2) | 1846 | 4.2 | (4.0; 4.4) |
CI, confidence interval; HCC, hepatocellular carcinoma; ICC, intrahepatic cholangiocarcinoma. * Per 100,000 persons, age-standardised to the 2013 European standard population.