Figure 1.

Schematic illustration of NKA structure. NKA contains the α, β and γ subunits. The extracellular region⁸⁹⁷ DVEDSYGQQWTYEQR⁹¹¹ (DR region) of the α subunit is associated with the β subunit. The hexagons (yellow and red) depicted above are two binding sites for α-synuclein fibrils and spherical amyloid β (Aβ) oligomers that are close to the DR region [25,26].