Table 3.
Anxiolytic drugs used and recommended in the Italian pediatric haemato-oncology setting.
| Anxiolytic Drug | Age | Recommended Dose | Side Effects |
|---|---|---|---|
| Lorazepam (approved for ≥ 18) * |
>10 years old | 0.5–2 mg | Sedation, fatigue, dizziness, anticholinergic side effect, and paradoxical activation (in younger children) |
| Delorazepam (approved for ≥ 18) * |
>3 years old | 10 drops/day | / |
| Alprazolam (approved for ≥ 18) * |
>14 years old | 1 mg × 3 times/die Cp 0.25 2 times/die |
/ |
| Clonazepam (approved for ≥ 18) * |
>6 years old | 0.5 mg/die | Sedation, confusion, and paradoxical activation, particularly in youth with central nervous system dysfunctions |
* Note: the approval of the drugs refers to the EMA.