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. 2022 Dec 19;14(24):6250. doi: 10.3390/cancers14246250

Table 1.

Effect of an abundance of selected bacteria in gut microbiome on the risk of death and progression in patients undergoing immunotherapy in Cox multivariate analysis.

Survival Factor Coefficient β p-Value Hazard Ratio (95% CI)
OS Ruminococcaceae 3.0 0.0002 20.8 (4.3 to 100.6)
Enterobacteriaceae 1.1 0.02 3.1 (1.1 to 8.5)
Overall Model Fit: Chi-squared = 23.2, p < 0.0001
PFS Butyriciococcaceae 2.6 0.001 13.4 (2.7 to 66.1)
Clostridiaceae 1.3 0.03 3.9 (1.1 to 13.2)
Eubacteriaceae 2.0 0.003 7.3 (2.0 to 26.5)
Overall Model Fit: Chi-squared = 16.8, p = 0.0008