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. 2022 Dec 8;12(12):3094. doi: 10.3390/diagnostics12123094

Table 2.

Main predictors of depressive symptoms and their correlations with chronic diabetes.

Author (Year) Predictors and Correlates of Depressive Symptoms among DM Patients
Abdelghani et al. (2021) [34] Poor physical component summary (OR = 0.88, 95% CI = 0.78–0.99, p = 0.045)
Poor mental component summary (OR = 0.84, 95% CI = 0.74–0.96, p = 0.009)
Abdoli et al. (2021) [38] Female gender (OR = 1.83, 95% CI = 1.26–2.66, p = 0.0008)
Younger (OR = 1.02, 95% CI = 1.01–1.04, p < 0.0001)
Single (OR = 1.47, 95% CI = 1.09–1.97, p = 0.014)
Education level (OR = 2.74, 95% CI = 1.59–4.73, p = 0.0032)
Higher HbA1c (OR = 1.26, 95% CI = 1.12–1.43, p < 0.000)
Lower daily time-in-range blood glucose (OR = 1.01, 95% CI = 1– 1.02, p = 0.0002)
Difficulties accessing healthy food (OR = 1.39, 95% CI = 1.05–1.85, p = 0.019)
Changes in diabetes self-care behaviors (OR = 1.70, 95% CI = 1.27–2.27, p < 0.0001)
Fear of approaching diabetes facilities (OR = 1.33, 95% CI = 1.05–1.77, p = 0.0458)
Alaqeel et al. (2021) [39] Female sex (aOR = 4.55, 95% CI = 1.80–11.48, p = 0.001)
Uncontrolled HbA1c level (aOR = 7.12, 95% CI = 1.93–26.32, p = 0.003)
Longer diabetes duration (DM duration of ≥ 5 years aOR = 4.82, 95% CI = 1.07–21.65, p = 0.040)
Ajele et al. (2022) [35] Direct relationship between depression and psychological well-being (β = 36, p < 0.05)
Negative relationship between depression and diabetes distress (β = −0.47, p < 0.05)
Basit et al. (2021) [40] Fear of COVID-19 (OR = 4.68, 95% CI = 0.96–22.68, p = 0.05)
Chao et al. (2021) [30] Female sex (aOR = 1.4, 95% CI = 1.1–1.7)
Obesity (aOR = 1.3, 95% CI = 1.0–1.5)
Choudhary et al. (2022) [42] Female (p < 0.0001)
Cusinato et al. (2021) [45] Lower time in glucose range (p = 0.012)
Kim & Kim (2022) [46] Decreased physical activity (aOR = 1.34, 95% CI = 1.15–1.55)
Decreased sleep time (aOR = 1.87, 95% CI = 1.56–2.24)
Increased junk food or carbonated beverages consumption (aOR = 1.48, 95% CI = 1.11–1.99)
Increase in frequency of food delivery consumption (aOR = 1.54, 95% CI = 1.15–2.08)
Increased alcohol consumption (aOR = 2.46, 95% CI = 1.62–3.71)
Increase in cigarette consumption (aOR = 1.92, 95% CI = 1.27–2.90)
Kim et al. (2022) [33] Worries associated with COVID-19 and depression score (r = 0.46, p = 0.000)
Moradian et al. (2021) [48] COVID-19-related fear (p < 0.001)
Musche et al. (2021) [29] COVID-19-related fear (p = 0.006)
Myers et al. (2021) [32] Female (p < 0.001)
Youngest age group 18–34 years (p < 0.001)
Rechenberg & Koerner, (2022) [37] Poorer general treatment-related quality of life (p < 0.001)
Sayed et al. (2022) [44] Higher HbA1c level (p < 0.05)
Silveira et al. (2021) [43] Difficulty accessing diabetes supplies (p < 0.05)
Higher HbA1c level (p < 0.05)
Sisman et al. (2021) [27] Individuals with T2D (p = 0.03)
Souza et al. (2021) [41] Female sex (OR = 2.5, 95% CI = 1.33–4.72, p = 0.004)
Single (OR = 4.1, 95% CI = 2.34–7.13, p < 0.001)
No religion (OR = 2.2, 95% CI = 1.34–3.54, p = 0.002)
History of anxiety and/or depression (OR = 2.6, 95% CI = 1.64–4.14, p < 0.001)
Reduced monthly income during the pandemic period (OR = 1.9, 95% CI = 1.18–3.11, p = 0.008)
Reduced work or remote study (OR = 1.9, 95% CI = 1.18–3.11, p = 0.008)
Wańkowicz et al. (2021) [36] Female sex (p = 0.013)

AOR = adjusted OR, DM = diabetes mellitus, T2D = type 2 diabetes.