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. 2022 Dec 15;11(24):4070. doi: 10.3390/cells11244070

Figure 5.

Figure 5

SS non-survivor heatmap representing Spearman’s rank correlation coefficients (−1 to +1) among clinical variables analyzed. Red color indicates a negative correlation, and blue color indicates a positive correlation between compared parameters. (A) First sample obtained (during the first 24 h of patient admission in the ICU); (B) second sample obtained (after 3 days in the ICU); (C) third sample (after 5 days in the ICU). Abbreviations: CircHist: circulating histones; CitrH3: citrullinated H3; APC; activated protein C; SOFA: Sequential (sepsis-related) Organ Failure Assessment; APTT: activated partial thromboplastin time; PCR: reactive C protein; PCT: procalcitonin; PMN: polymorphonuclear cells; Plaq: platelets; Quick: quick SOFA; DD: D-dimer; TropUS: ultrasensitive troponin; FuncProtC: functional C protein; APACHE II: Acute Physiology and Chronic Health Disease Classification System II; Protromb Tot: total prothrombin; LAC6H: lactate after 6 h ICU entrance. The number of subjects analyzed was as follows: control (n = 10); intensive care unit (ICU) (n = 5); sepsis (n = 10); septic shock (SS) (n = 15).