Table 3.
Comparison of characteristics between resected and unresected patients in Groups 1, 2, and 7.
| Unresected | Resected | Univariate Analysis (p-Value) | Multivariate Analysis | ||
|---|---|---|---|---|---|
| p-Value | Odds Ratio (95%CI) | ||||
| Patients’ number | 193 | 66 | |||
| Female, n (%) | 94 (48.7) | 40 (60.6) | 0.045 | <0.01 | 2.36 (1.26–4.45) |
| Age, median (range), years | 73 (34–105) | 72 (42–86) | 0.78 | ||
| Age, ≥75 years old, n (%) | 87 (45.1) | 25 (37.9) | 0.32 | 0.20 | 0.66 (0.34–1.26) |
| Group 7 (vs. Group1,2), n (%) | 7 (3.6) | 10 (15.2) | <0.01 | 0.04 | 3.31 (1.08–10.11) |
| Diabetes mellitus, n (%) | 43 (22.3) | 16 (9.1) | 0.74 | ||
| Any of the 3 diseases (diabetes mellitus, hypertension, hyperlipidemia), n (%) | 105 (54.4) | 40 (24.2) | 0.09 | ||
| History of other cancer, n (%) | 26 (13.5) | 11 (16.7) | 0.39 | ||
| History of heavy drinking (ethanol ≥100 g/day) | 7 (3.6) | 3 (4.5) | 0.72 | ||
| History of smoking, n/N (%) | 96/192 (50) | 27 (40.9) | 0.25 | ||
| Family history of PC (≤1st degree), n/N (%) | 13/145 (9.0) | 3/50 (6) | 0.77 | ||
| IPMN-derived carcinoma, PDAC, n | 3, 190 | 5, 61 | 0.03 | 0.10 | 3.81 (0.78–18.67) |
| Localization of PC tail, n (%) | 36 (18.7) | 6 (9.1) | 0.08 | ||
| BMI, median (range), kg/mm2 | 21.1 (14.3–35.2) n = 191 | 23.0 (15.0–32.7) | <0.001 | ||
| BMI (kg/mm2) ≥ 18.5, n/N (%) | 146/191 (76.4) | 62/66 (93.9) | <0.01 | 0.02 | 3.76 (1.24–11.43) |
| CA19-9, median (range), U/mL | 1352 (1–215,454) n = 190 | 165 (1–4941) | <0.001 | ||
| CA19-9 (U/mL) ≥ 425 | 109/190 (5 7.4) | 17/66 (25.8) | < 0.001 | <0.001 | 0.31 (0.16–0.59) |
| AMY (U/L), median (range), | 62.0 (12–902) | 68.5 (24–664) | 0.15 | ||
Groups 1 and 2 included patients with pancreatic cancer (PC) identified through symptoms of biliary obstruction and symptoms that were not in group 1, respectively. Group 7 included patients with PC identified through abdominal ultrasonography (US) during medical checkup of asymptomatic individuals. The value of CA19-9, 425 (U/mL) was based on the median values of patients in Groups 1, 2, and 7. We had several data defectiveness, and “n” in the table shows the analyzed patient number and “n/N“ show positive number/analyzed number. IPMN: intraductal papillary mucinous neoplasm, PDAC: pancreatic ductal adenocarcinoma, BMI: body mass index, CA19-9: serum level of carbohydrate antigen 19-9, AMY: serum level of amylase, CI: confidence intervals.