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. 2022 Nov 23;44(12):5848–5865. doi: 10.3390/cimb44120398

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Gene expression pattern with each GSE dataset and clustering of DEGs heat map of overlapping genes. (A) The volcano plot shows gene expression distribution of the microarray data in GSE36295, (B) GSE36693, and (C) GSE65216. The data was cut-off based on p-value < 0.01 and fold change (FC) log > 1. X-axis and y-axis present fold change log and log-transformed p-value, respectively. (D) Venn diagram for intersection of all up-regulated and down-regulated DEGs of GSE36295, GSE36693, and GSE65216 using the FunRich program. (E) Heat map exhibiting expression changed genes of up-regulated and down-regulated DEGs using GraphPad.