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. 2022 Nov 23;44(12):5848–5865. doi: 10.3390/cimb44120398

Figure 4.

Figure 4

Comparison of DEGs expression between non-TNBC and TNBC patients or cell lines. (A) The comparison of up-regulated DEGs, MCM4, CDC7, CCNB2, and CHEK1, in Healthy, non-TNBC, and TNBC from GSE65216. (B) The comparison of down-regulated DEGs, CXCL12, IL6ST, and IGF1, in Healthy, non-TNBC, and TNBC. (C) The mRNA expression comparison of up-regulated DEGs, MCM4, CDC7, CCNB2, and CHEK1, in non-TNBC cells and TNBC cells, which are MCF-7 and MDA-MB231. (D) The mRNA expression comparison of down-regulated DEGs, CXCL12, IL6ST, and IGF1, in non-TNBC cells and TNBC cells, which are MCF-7 and MDA-MB231. Columns are presented with the mean of SEM. Statistical analysis using one-way ANOVA was performed in (A,B), and t-test performed in (C,D); * p < 0.05, ** p < 0.005, *** p < 0.0005, **** p < 0.0001 vs. control in each group, n.s.: nonsignificant.