TABLE 2.
Adhesion to and internalization by epithelial cells of capsulated parent strains and their corresponding noncapsulated variantsa
| Parental and noncapsulated variant pairs | % Adhesion
|
% Invasion
|
||
|---|---|---|---|---|
| Ileocecal cells | Bladder cells | Ileocecal cells | Bladder cells | |
| K21a | 16.5 | 11.2 | 2.4 | 0.4 |
| K21/3 | 31.7 | 33.0 | 7.8 | 0.8 |
| K26 | 60.0 | 15.0 | 0.7 | 0.2 |
| K26/1 | 57.4 | 15.5 | 1.8 | 0.6 |
| K36 | 14.0 | 21.5 | 2.9 | 0.4 |
| K36/3 | 30.6 | 49.0 | 4.3 | 0.8 |
| K50 | 42.0 | 40.0 | 2.7 | 0.9 |
| K50/3 | 99.0 | 81.0 | 9.5 | 1.5 |
a
Confluent monolayers of ileocecal (HCT-8) and bladder (T24) epithelial cell lines were exposed to the indicated Klebsiella strains, and percents adhesion to and internalization by the cell lines were estimated as described in Materials and Methods. Data shown represent mean values of at least triplicate experiments; standard deviations of the mean values did not exceed 20%.