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. 2022 Dec 16;14(24):6221. doi: 10.3390/cancers14246221

Table 1.

Ibanez complication grading scheme.

Grade Nature of the Complication Example of Complication
1 Any medical or surgical non–life-threatening deviation from normal operative/postoperative course, requiring either non-invasive treatment or no treatment at all.
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    Medical: acute urinary retention, non-infectious diarrhea

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    Surgical: CSF leak not requiring reoperation, seizures or CNS infections managed with appropriate treatments

2 Medical or surgical complication requiring invasive treatment, with or without general anesthesia.
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    Medical: deep vein thrombosis requiring vena cava filter

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    Surgical: wound revision, CSF leak requiring surgical repair or drainage

3 Medical or surgical life-threatening complications requiring ICU care, with either single or multi-organ failure.
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    Medical: acute myocardial infarction, lung distress, renal failure

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    Surgical: acute hydrocephalus requiring drainage, severe meningitis, iatrogenic ischemia

4 Any medical or surgical complication leading to operative or postoperative death. Perioperative death as the ultimate endpoint

CSF: cerebrospinal fluid, CNS: central nervous system, ICU: intensive care unit.