Table 3.
Comparison of the mean values of clinical variables across the three genotypes of the ABCA1 C69T gene.
| CC (n = 74) |
TT (n = 292) |
CT (n = 284) |
CC vs. TT p-Value a |
CC vs. CT p-Value a |
TT vs. CT p-Value a |
p-Value b | |
|---|---|---|---|---|---|---|---|
| HbA1c % | 5.27 (0.55) | 5.24 (0.46) | 5.28 (0.52) | 0.7 a2 | 0.816 a2 | 0.317 a2 | 0.606 b2 |
| FPG | 4.28 (0.87) | 4.48 (1.05) | 4.49 (0.93) | 0.009 a2 | 0.009 a2 | 0.942 a2 | 0.022 b2 |
| PG (1 h) | 6.26 (1.88) | 6.78 (2.13) | 6.8 (2.19) | 0.042 a2 | 0.049 a2 | 0.927 a2 | 0.107 b2 |
| TC (mmol/L) | 4.94 (0.95) | 4.78 (0.94) | 4.85 (0.95) | 0.194 a2 | 0.730 a2 | 0.224 a2 | 0.314 b2 |
| HDL-c (mmol/L) | 1.35 (0.26) | 1.35 (0.28) | 1.33 (0.29) | 0.88 a2 | 0.364 a2 | 0.241 a2 | 0.43 b2 |
| TG (mmol/L) | 1.36 (0.92) | 1.21 (0.77) | 1.37 (1.02) | 0.398 a2 | 0.844 a2 | 0.11 a2 | 0.262 b2 |
| LDL (mmol/L) | 3.31 (0.86) | 3.2 (0.84) | 3.25 (0.86) | 0.334 a2 | 0.818 a2 | 0.265 a2 | 0.437 b2 |
| LDL:HDL | 2.56 (0.9) | 2.46 (0.76) | 2.56 (0.87) | 0.732 a1 | 0.785 a1 | 0.300 a1 | 0.59 b1 |
Data are presented as mean (SD). FPG, fasting plasma glucose; HbA1c, glycated hemoglobin; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; PG, plasma glucose; TC, total cholesterol; TG, triglycerides. a Differences in measurements were analyzed using the t-test (a1) or Mann–Whitney test (a2). b Differences in measurements were analyzed using the one-way ANOVA (b1) or Kruskal–Wallis (b2) test. Bold indicates significant differences in mean values.