Table 4.
Comparison of laboratory parameters and inflammatory markers between pre-COVID and peri-COVID groups in PA patients.
| Laboratory Parameters |
Pre-COVID n = 237 |
Peri-COVID n = 196 |
p | COVID-19 n = 28 |
Non-COVID-19 n = 168 |
p |
|---|---|---|---|---|---|---|
| WBC (×103/μL) | 13.25 ± 5.84 | 13.64 ± 6.71 | 0.047 * | 16.07 ± 7.94 | 13.24 ± 6.42 | 0.082 |
| NEU (×103/μL) | 10.81 ± 5.86 | 11.17 ± 6.45 | 0.513 | 12.07 ± 7.48 | 11.02 ± 6.27 | 0.427 |
| LYM (×103/μL) | 1.65 ± 0.94 | 1.53 ± 1.26 | 0.545 | 1.99 ± 1.18 | 1.45 ± 1.26 | 0.037 * |
| MON (×103/μL) | 0.86 ± 0.48 | 0.97 ± 1.21 | 0.242 | 1.84 ± 2.83 | 0.82 ± 0.51 | 0.069 |
| PLT (×103/μL) | 217.50 ± 115.79 | 212.97 ± 113.79 | 0.683 | 237.43 ± 143.72 | 208.89 ± 107.99 | 0.220 |
| MCV (fL) | 89.67 ± 8.68 | 93.57 ± 7.56 | <0.001 * | 96.02 ± 7.85 | 93.17 ± 7.46 | 0.065 |
| RDW | 13.24 ± 1.88 | 13.51 ± 1.48 | 0.101 | 14.20 ± 1.36 | 13.39 ± 1.47 | 0.007 * |
| NLR | 8.46 ± 6.01 | 10.24 ± 8.61 | 0.015 * | 7.85 ± 6.17 | 10.64 ± 8.91 | 0.045 * |
| PLR | 160.35 ± 112.62 | 171.72 ± 105.24 | 0.282 | 114.23 ± 112.56 | 176.30 ± 103.62 | 0.136 |
| MLR | 0.61 ± 0.38 | 0.78 ± 0.77 | 0.005 * | 1.04 ± 1.41 | 0.74 ± 0.60 | 0.278 |
| dNLR | 4.66 ± 2.93 | 6.08 ± 6.68 | 0.006 * | 4.40 ± 3.34 | 6.36 ± 7.05 | 0.152 |
| AISI | 1899.28 ± 2994.76 | 2075.22 ± 280372 | 0.531 | 2352.12 ± 2240.83 | 2029.07 ± 2889.99 | 0.574 |
| SIRI | 7.76 ± 8.13 | 9.28 ± 10.98 | 0.109 | 10.63 ± 11.35 | 9.06 ± 10.93 | 0.438 |
| SII | 1870.92 ± 2000.38 | 2072.69 ± 2193.28 | 0.318 | 1689.64 ± 1460.38 | 2136.53 ± 2289.87 | 0.319 |
| MCVL | 70.26 ± 37.17 | 90.65 ± 67.15 | <0.001 * | 65.04 ± 34.33 | 94.91 ± 70.33 | 0.029 * |
| IIC | 10.73 ± 8.71 | 13.03 ± 10.86 | 0.006 * | 11.04 ± 8.99 | 13.36 ± 11.31 | <0.001 * |
* p < 0.05—statistically significant; WBC—leukocytes, NEU—neutrophils, LYM—lymphocytes, MON—monocytes, PLT—platelets, MCV—mean corpuscular volume, RDW—erythrocyte distribution width, NLR—neutrophil–lymphocyte ratio, PLR—platelet–lymphocyte ratio, MLR—monocyte–lymphocyte ratio, dNLR—derived neutrophil–lymphocyte ratio, AISI—the aggregate index of systemic inflammation, SIRI—systemic inflammatory response index, SII—systemic immune-inflammation index, MCVL—average corpuscular volume to lymphocytes ratio, IIC—cumulative inflammatory index.