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. 2022 Dec 16;13(12):2392. doi: 10.3390/genes13122392

Table 1.

Demographic and clinical features of multiple sclerosis patients of the multiplex family.

Characteristics of MS Patients Individual II-6 Individual II-15 Individual II-11 Individual III-5
Gender Female Female Male Male
Age (years) 66 50 63 32
MS course SP SP SP RR
Age at MS onset (years) 41 33 33 25
Age at MS diagnosis (years) 49 35 39 31
Disease duration (years) 24 17 30 7
EDSS 6.5 7.0 6.5 2.0
MSSS 6.362 7.765 5.608 3.17
MS treatment IFN 1β No treatment Chronic steroid GA

RR: relapsing-remitting; SP: secondary-progressive. IFN 1β: interferon β-1 a; GA: glatiramer acetate; EDSS: expanded disability status scale; MSSS: multiple sclerosis severity scale.