Table 6.
Distribution of the rs3892097 genotypes of the CYP2D6 gene in the Finno-Permic populations of the Russian Federation.
| Population | N | GG | GA | AA | Minor Allele Frequency (95% CI) |
χ2 | Deviations from HWE, p | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Observed (N) | Expected (N) | % | Observed (N) | Expected (N) | % | Observed (N) | Expected (N) | % | |||||
| Veps | 60 | 48 | 48.6 | 80 | 12 | 10.8 | 20 | 0 | 0.6 | 0 | 10% (5.27–16.82) | 0.741 | 0.389 |
| Karelian | 60 | 43 | 44.2 | 71.67 | 17 | 14.6 | 28.33 | 0 | 1.2 | 0 | 14.17% (8.47–21.71) | 1.634 | 0.201 |
| Udmurt | 96 | 65 | 67.5 | 67.71 | 31 | 26 | 32.29 | 0 | 2.5 | 0 | 16.15% (11.24–22.13) | 3.559 | 0.059 |
| Bessermyan | 94 | 68 | 69.8 | 72.34 | 26 | 22.4 | 27.66 | 0 | 1.8 | 0 | 13.83% (9.24–19.60) | 2.421 | 0.119 |
| Mordovian (total) | 136 | 94 | 97.2 | 69.12 | 42 | 35.5 | 30.88 | 0 | 3.2 | 0 | 15.44% (11.36–20.29) | 4.535 | 0.033 |
| Erzya | 78 | 55 | 56.7 | 70.51 | 23 | 19.6 | 29.49 | 0 | 1.7 | 0 | 14.74% (9.58–21.30) | 2.333 | 0.127 |
| Moksha | 35 | 22 | 23.2 | 62.86 | 13 | 10.6 | 37.14 | 0 | 1.2 | 0 | 18.57% (10.28–29.66) | 1.821 | 0.177 |
| Komi (total) |
94 | 74 | 75.1 | 78.72 | 20 | 17.9 | 21.28 | 0 | 1.1 | 0 | 10.64% (6.62–15.95) | 1.332 | 0.248 |
| Izhemsk | 47 | 41 | 41.2 | 87.23 | 6 | 5.6 | 12.77 | 0 | 0.2 | 0 | 6.38% (2.38–13.38) | 0.218 | 0.640 |
| Syktyvdinsk | 47 | 33 | 34 | 70.21 | 14 | 11.9 | 29.79 | 0 | 1 | 0 | 14.89% (8.39–23.72) | 1.439 | 0.230 |