Table 1.

Reported systemic antibiotic prescribing rates in outpatient wound care.

Reference	Country	Wound Types *	% of Patients Prescribed Antibiotics	Intervention Implemented	% of Patients Prescribed Antibiotics after Intervention	Notes on Prescribing
Serena et al. (2021) [11]	USA	DFU PU VLU SSI Others	25.7%	Moleculight® fluorescence imaging of bacterial location and load	-	Prescription rate was taken at time of enrolment in the single time-point study and was based on standard of care (pre-intervention); postinterventional rate was not recorded
Price (2020) [16]	UK	DFU	67%	Moleculight® fluorescence imaging of bacterial location and load	22.1% **	Healing rates improved by 23% at 12 weeks (from 38% to 49%)
Gürgen (2014) [7]	Norway	DFU VLU AU A-VU PU unspecified	53.3%	-	-	Prospective observational study of 105 patients, who had received at least one course of systemic antibiotics at any point during care for their wound
Öien et al. (2013) [24]	Sweden	DFU	71%	National quality assessment registry for ulcer care	29% p = 0.0001	Median healing time decreased by 83 days in 3 years (adjusted for ulcer size)
		VLU
		AU
		A-VU PU unspecified
Howell-Jones et al. (2006) [22]	UK	DFU VLU AU A-VU PU	68.3%	-	-	% of patients who received at least one course of systemic antibiotics during the duration of the wound, compared to 29.3% in non-wound patients (p < 0.0001)
Tammelin et al. (1998) [23]	Sweden	PU Foot and leg ulcers Unspecified ulcers	60.1%	-	-	% of patients (n = 665) that had received at least one course of systemic antibiotics in the last 6 months for their wound

* DFU: Diabetic Foot Ulcer, VLU: Venous Leg Ulcer, AU: Arterial Ulcer, VU: Venous Ulcer, A-VU: Arterial Venous Ulcer, PU: Pressure Ulcer/Injury. ** Systemic antibiotics prescribed at any point during care for their wound.