TABLE 2.

IL-12 concentrations in supernatant fluids from PBMC cultures^a stimulated by S. mutans and L. casei

Bacterial concn (ml−1)	IL-12 concn (ng/ml)b in culture stimulated with:		P
	S. mutans	L. casei
PBMC control	0.00 (0.00–0.00)	0.00 (0.00–0.00)	0.8820
104	1.36 (0.37–4.99)	0.00 (0.00–0.01)	<0.0001
105	4.87 (1.32–17.93)	0.01 (0.02–0.05)	<0.0001
106	3.46 (0.87–13.69)	0.23 (0.06–0.92)	0.0089

^aPBMC (10⁶/ml) were stimulated with 10⁴ to 10⁶ S. mutans (n = 11) and L. casei (n = 10) bacteria per ml. The supernatant fluids were harvested after 7 days, and IL-12 concentrations were assayed by ELISA. 

^bMean (95% CI).