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. 2022 Dec 5;13(12):2292. doi: 10.3390/genes13122292

Figure 2.

Figure 2

Characteristics of 180 Cavalier King Charles Spaniels (CKCS) at two low diversity loci as assayed using genotyping arrays. (a) Minor allele frequency (MAF) throughout the NEBL gene region chr2:11,650,000 to chr2:12,650,000, (b) MAF throughout the HDGFL1 region chr7:40,745,000 to chr7:41,746,000. (c) Regional pairwise linkage disequilibrium by r2 (LD) (grey dots) with the NEBL3 variant at chr2:11 979 724 (red dot) and other NEBL variant loci shown as blue dots. (d) Regional pairwise LD (grey dots) with the HDGFL1 variant predictor chr7:41 248 384 (coding variant at 7:41 245 057) (blue dot). Shaded regions represent the respective gene spans.