Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 2;13(12):2276. doi: 10.3390/genes13122276

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Activation of the cancer-associated fibroblast subset in EOC progression. (a,b) T-SNE view of fibroblasts, colored by cell types (a) and sample groups (b). (c) General stromal markers for fibroblasts and representative markers for ACTA2-positive fibroblasts. (d) Functional analysis of differentially expressed genes among the two subtypes of fibroblasts. (e) Vlnplots show the expression of genes that regulate ECM formation and components across the two fibroblast subtypes. (f) Pseudotime trajectory of the two subgroups of fibroblasts inferred by Monocle 2.