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Domain organization of ITAFs involved in type I IRES-driven translation. Secondary structure of PV IRES (Mahoney strain) with highlighted functionally important sequences. Nucleotides that are protected or modified in the presence of selected proteins are marked. Note that while there is no direct evidence regarding UNR binding site on PV IRES, an approximation was made from the data obtained for the HRV-2 IRES.
