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. 2022 Dec 11;23(24):15705. doi: 10.3390/ijms232415705

Figure 8.

Figure 8

Antifibrotic mechanism of TRIB3 mediation of pulmonary fibrosis through inhibition of lung fibroblast activation. TRIB3 inhibits the transformation of pulmonary fibroblasts into myofibroblasts through interaction with ATF4 and inhibiting its expression.