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. 2022 Dec 22;17(12):e0279522. doi: 10.1371/journal.pone.0279522

Fig 4. Synergy calculations of the combined effects between enzalutamide and ribociclib treatments.

Fig 4

MDA-MB-231 (a), MCF 7 (b), and MDA-MB-468(c) cells were treated with indicated concentrations of the enzalutamide plus ribociclib (0.5, 2, 5, 10, 15, 20, 25, 35, 45, and 60 μM of enzalutamide in combination with 5 and 25 μM of ribociclib) for 48 hr. Cell viability was investigated by MTT assay. The degree of antagonism or synergism between two drugs has been shown by a color bar (blue color indicates synergism).