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. 2022 Dec 12;23(24):15759. doi: 10.3390/ijms232415759

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

MiRNA, lncRNA, circRNA, and piRNA are associated with proliferation, apoptosis, metastasis, autophagy, stemness, and drug resistance in BC. Dysregulation of ncRNAs due to aberrant crosstalk between methylation modification and ncRNAs is associated with malignant behavior in BC, such as proliferation (miR-375, lncRNA EPIC1, circBACH2. miR-200a-5p, miR-125b, miR-10b, miR-29b-1-5p), apoptosis (lncRNA APOC1P1-3, LNC942. lncRNA PYCARD-AS1), metastasis (miR-146a-5p, miR-29a, lncRNA HUMT, lncRNA MYMA, LINC00518, and lncRNA HOTAIR. miR-200c/141, miR-205, miR-124, and LINC00472), autophagy (miR-125a), stemness (piR-823, miR-34c, miR-200c-141, and miR-203), and drug resistance (miR-663, miR-221-3p, lncRNA H19, lncRNA UCA1. miR-375, miR-27b, miR-320a, miR-149, miR-375, lncRNA GAS5, lncRNA MEG3, lncRNA SNHG10).