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. 2022 Dec 9;23(24):15603. doi: 10.3390/ijms232415603

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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DNA methylation analysis of FASN promoter. (A) Distribution of DNA methylation at the FASN locus in the representative cancer BLCA. (B) DNase-seq data in eleven cancers obtained from the ENCODE database were visualized using the integrative genomics viewer, coordinates were located at the FASN locus, and the peaks of the target are shown in shaded areas. (C) Differences in aggregated methylation of seven methylation probes (cg24715260, cg14521508, cg17462356, cg20276947, cg18009376, cg03386722, cg11958594) of FASN in multiple cancers. (* p < 0.05, ** p < 0.01, **** p < 0.001).